Study tests if Two-Drug maintenance beats One-Drug after stem cell transplant for myeloma

NCT ID NCT05271630

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 69 people with multiple myeloma who had a stem cell transplant. It compares those who take one maintenance drug versus two drugs (an immunomodulatory agent plus a proteasome inhibitor) to see which keeps the cancer away longer. The goal is to learn if the two-drug combo leads to better outcomes, like turning cancer markers from positive to negative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Immunomodulatory agent and proteasome inhibitor

What this could lead to

If successful, this could help doctors choose the best maintenance therapy to keep multiple myeloma in remission longer after a stem cell transplant.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove one treatment is better. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States