New combo therapy aims to freeze and burn liver cancer

NCT ID NCT07159048

Recruiting now Disease control Sponsor: Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study tests a device that uses both freezing and heating to destroy liver tumors in people with liver cancer or colorectal cancer that has spread to the liver. The goal is to see if this approach improves how long patients live without their cancer growing, and whether it activates the immune system. About 120 adults will take part across multiple hospitals.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Multimodal Tumor Thermal Therapy System (device combining cryotherapy and radiofrequency heating)
What this could lead to: If successful, this approach could offer a more effective way to destroy liver tumors and potentially boost the body's immune response against cancer.
What could go wrong: This is an early-stage trial with only 120 participants, so results may not apply to everyone. The therapy is complex and may not work better than standard ablation methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma metastasis from malignant tumor of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER LIVER METASTASIS HEPATOCELLULAR CARCINOMA

Contacts and locations

Locations

Fudan University
RECRUITING

Shanghai, Shanghai Municipality, China

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