Anti-Aging drug sirolimus put to the test in seniors

NCT ID NCT06727305

Recruiting now Knowledge-focused Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing the drug sirolimus in 60 healthy adults aged 65 and older to see how the body processes it and how it affects aging-related markers. Participants take sirolimus tablets daily for several weeks, with dose adjustments to reach a target blood level. The goal is to gather essential data for future trials that might use sirolimus to slow aging and prevent chronic diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sirolimus (oral tablet)
What this could lead to: If successful, this study could provide the necessary data to design larger trials testing whether sirolimus can slow aging and prevent age-related diseases.
What could go wrong: This is an early-phase study with only 60 participants, focused on measuring drug levels and markers, not on proving any anti-aging benefit. The results may not lead to a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING

Contacts and locations

Locations

UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

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