Off-the-Shelf immune cells take on tough blood cancers
NCT ID NCT06552416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests a new treatment called MT-401-OTS for people with relapsed acute myeloid leukemia or high-risk myelodysplastic syndromes. The therapy uses donor immune cells specially trained to attack cancer, and is given as a one-time infusion. The main goals are to check safety and find the right dose, while also seeing if it helps control the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City of Hope Center (City of Hope National Medical Center, City of Hope Medical Center)
RECRUITINGDuarte, California, 91006, United States
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KU Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Frailty check may steer safer cancer care for seniors
- Can a different immune drug cut viral infections after stem cell transplants?
- Supercharged donor cells aim to stop leukemia return after transplant
- Worldwide data pool could pave the way for mitochondrial disease trials
- Engineered immune cells take aim at Hard-to-Treat leukemia
- New drug cocktail aims to boost transplant success in tough leukemias