Could a fluid from stem cells ease knee pain without surgery?
NCT ID NCT07157891
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase trial tests whether injecting a fluid made from stem cells (called secretome) mixed with growth factors from the patient's own blood can safely reduce knee pain and improve function in people with mild knee osteoarthritis. The study will enroll 25 adults aged 30-55 with early-stage arthritis. Researchers will monitor pain, stiffness, and any side effects over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MSC-derived secretome (cell-free fluid from stem cells) combined with plasma rich in growth factors (PRGF) from the patient's own blood
What this could lead to
If it works, this could point toward a non-surgical, cell-free treatment to ease knee pain and improve function in early osteoarthritis.
What could go wrong
This is a very early, small trial (25 people) testing safety first. The treatment may not reduce pain or repair cartilage, and joint injections carry infection or irritation risks.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.