Could a fluid from stem cells ease knee pain without surgery?

NCT ID NCT07157891

Not yet recruiting Symptom relief Sponsor: University of the Punjab Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests whether injecting a fluid made from stem cells (called secretome) mixed with growth factors from the patient's own blood can safely reduce knee pain and improve function in people with mild knee osteoarthritis. The study will enroll 25 adults aged 30-55 with early-stage arthritis. Researchers will monitor pain, stiffness, and any side effects over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MSC-derived secretome (cell-free fluid from stem cells) combined with plasma rich in growth factors (PRGF) from the patient's own blood
What this could lead to: If it works, this could point toward a non-surgical, cell-free treatment to ease knee pain and improve function in early osteoarthritis.
What could go wrong: This is a very early, small trial (25 people) testing safety first. The treatment may not reduce pain or repair cartilage, and joint injections carry infection or irritation risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARTILAGE DEGENERATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ankle injury Knee Injuries osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARTILAGE DEGENERATION KNEE INJURY OSTEOARTHRITIS (OA)

More trials for these conditions

Other studies related to the condition(s) this trial covers.