Scientists hunt for clues to MS severity

NCT ID NCT03369106

Ongoing Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find a combination of markers—from genetics, immune system, and brain scans—that are linked to how severe multiple sclerosis (MS) becomes. Researchers will follow 120 people with MS and their siblings who also have the condition. Participants undergo neurological exams, cognitive tests, and MRI scans to track disability and brain changes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better predict how multiple sclerosis will progress in a patient, leading to more personalized care.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear markers, and results may not change care for years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

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Locations

CIC Neurosciences Institut du Cerveau et de la Moelle Epinière

Paris, 75013, France

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