New MRI-Guided radiation technique tested for breast cancer treatment

NCT ID NCT05731791

Ongoing Disease control Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of radiation therapy for women with early-stage breast cancer after lumpectomy. One group receives standard CT-guided radiation, while the other receives a newer MRI-guided approach. The goal is to see if MRI-guided radiation works just as well at preventing cancer from coming back. Only 17 women aged 50 and older with small tumors are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (CT-based or MRI-based)
What this could lead to: If successful, MRI-guided radiation could become a new standard option for breast cancer treatment, potentially reducing side effects while maintaining cancer control.
What could go wrong: This is a very small, early-phase study with only 17 participants, so results may not apply to all patients. The trial is not designed to prove superiority, only to show MRI is comparable to current CT-based treatment.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Weill Cornell Medicine

New York, New York, 10065, United States

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