Can MRI predict breast cancer treatment success?
NCT ID NCT03738553
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 36 times
Summary
This study looked at whether special MRI scans can detect early signs that anti-HER2 therapy is working in women with HER2-positive breast cancer. Thirteen participants received one dose of trastuzumab before surgery, and researchers compared MRI changes to immune cell levels in the tumor. The trial was terminated early, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Seattle Cancer Care Alliance
Seattle, Washington, 98109, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trastuzumab
What this could lead to
If successful, this could help doctors use MRI to quickly tell if anti-HER2 therapy is working, potentially guiding treatment decisions.
What could go wrong
This was a very small, terminated study with only 13 participants. The results may not apply to larger groups, and the approach may not prove reliable.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.