MRI peers into dental numbness: a new way to watch anesthesia?
NCT ID NCT07602686
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 6 times
Summary
This study uses a special dental MRI to watch how local anesthesia affects the mouth during dental procedures. About 102 adults will have their numbness and sensation tested right after numbing and again one hour later. The goal is to see if MRI can help measure how well dental numbing works.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 102 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult age 18 or older * Health status of American Society of Anesthesiologists (ASA) class 1 or 2 * Able to provide informed consent * Able to appear in person at OMRIC on the days indicated for the study Exclusion Criteria: * ASA class 3 or higher * Pregnant patients * Taking any medication that would affect pain perception or interact with local anesthetic * Allergic/history of adverse reaction to local anesthetic or any component in the local anesthetic * Paresthesia in the area of innervation of Cranial Nerve V3 * Active infection or abscess in the oral and maxillofacial region * History of temporomandibular disorder, maximum incisal opening less than 15mm * History of recent dental trauma (within the past 6 months) * Dental hypersensitivity * Claustrophobia and/or conditions of anxiety or motion disorder (for MRI purposes) * Metallic, electronic, or magnetic implants or devices classified as MR Unsafe or Conditional by the American College of Radiology * Unable to give informed consent
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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