MRI-Guided radiation could sharpen lung cancer treatment
NCT ID NCT06545747
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether using MRI scans to guide radiation therapy can improve outcomes for people with locally advanced non-small cell lung cancer. Participants receive radiation, chemotherapy, and immunotherapy. The study compares MRI-guided radiation to standard CT-guided radiation, aiming to reduce lung side effects and improve cancer control. About 490 people will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy (hypofractionated radiotherapy), chemotherapy (albumin-bound paclitaxel and cisplatin), and immunotherapy (consolidative immunotherapy)
- What this could lead to
- If successful, this approach could improve local tumor control and reduce lung side effects for people with advanced lung cancer, potentially leading to longer survival.
- What could go wrong
- This is still an early-phase 3 trial, so results are not guaranteed. The combination of treatments may cause significant side effects, and the benefit over standard care is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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