One-Week radiation for breast cancer: MRI precision may cut side effects
NCT ID NCT03936478
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new radiation approach for early breast cancer that uses real-time MRI guidance to deliver just three high-dose sessions over one week, instead of the usual several weeks. The goal is to see if this shorter treatment is safe, preserves the breast's appearance, and limits damage to healthy tissue. The trial enrolls people who have had a lumpectomy for early-stage breast cancer or certain precancers, and follows them for up to five years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI-guided partial breast irradiation (3 fractions of 8.2 Gy)
What this could lead to
If successful, this could offer a shorter, more precise radiation option for early breast cancer, potentially reducing side effects and improving cosmetic outcomes.
What could go wrong
This is a small phase 2 study with only 30 participants, so results may not apply to all patients. The long-term safety and effectiveness beyond 5 years are not yet known.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Wisconsin Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53705, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••