New MRI aims to spot cancer in salivary glands without a needle

NCT ID NCT04452162

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether advanced MRI techniques can distinguish cancerous from non-cancerous salivary gland tumors. Thirty adults with a salivary gland lesion will receive one research MRI scan with contrast before their scheduled surgery. The goal is to improve diagnosis and predict disease progression, potentially reducing the need for invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MRI with contrast dye
What this could lead to
If successful, this MRI technique could help doctors identify cancerous salivary gland tumors without needing a biopsy, guiding better treatment decisions.
What could go wrong
This is a small, early study (30 people) testing a new imaging method. It may not prove accurate enough to replace standard biopsy, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

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