New drug combo targets head and neck cancer with precision radiation

NCT ID NCT04105543

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 28 times

Summary

This early-phase study tested an experimental drug, CLR 131, that delivers radiation directly to cancer cells, combined with standard external beam radiation. The goal was to see if this combination is safe and can deliver a high dose of radiation to tumors in people whose head and neck cancer has come back. The study enrolled 12 participants and used imaging to measure how much radiation reached the tumor.

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Contacts and locations

Locations

  • UW Cancer Center Johnson Creek

    Johnson Creek, Wisconsin, 53038, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.