Blood test may spot lung cancer relapse months early

NCT ID NCT06443684

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 305 people with stage III non-small cell lung cancer who have specific genetic mutations. Researchers regularly test their blood for tiny traces of cancer DNA (minimal residual disease, or MRD) to see if it can predict when the cancer will come back. The goal is to find out if MRD testing is more accurate than standard scans for early detection of recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a blood test that warns of lung cancer returning months before scans detect it.

What could go wrong

This is an observational study, not a treatment trial. It may show MRD is not a reliable predictor, or results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Cancer Hospital of Harbin Medical University

    Harbin, Heilongjiang, China

  • First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, China

  • Hunan Cancer Hospital

    Changsha, Hunan, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250000, China

  • Shandong Provincial Hospital

    Jinan, Shandong, China

  • Shanghai Chest hospital

    Shanghai, Shanghai Municipality, China

  • Shanxi Cancer Hospital

    Taiyuan, Shanxi, China

  • The First Affiliated Hospital of Guangzhou Medical University

    Guangzhou, Guangdong, China

  • The First Affiliated Hospital of USTC / Anhui Provincial Hospital

    Hefei, Anhui, 230000, China

  • The First Affiliated Hospital of Xi 'an Jiaotong University

    Xi’an, Shanxi, China

  • The First Affiliated Hospital of Zhejiang University

    Hangzhou, Zhejiang, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450000, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China

  • Zhongshan Hospital Affiliated to Fudan University

    Shanghai, Shanghai Municipality, China