COVID-19 blood clot risk in MPN patients under microscope

NCT ID NCT04385160

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at 552 adults with myeloproliferative neoplasms (MPN) who also had COVID-19. Researchers wanted to see how often these patients developed blood clots, like pulmonary embolism. The goal was to understand what factors make COVID-19 worse for people with MPN.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand and manage COVID-19 risks in MPN patients.

What could go wrong

This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all MPN patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 Myeloproliferative Disorders myeloproliferative neoplasm thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • A.O.U. Città della Salute e della Scienza di Torino

    Torino, 10126, Italy

  • A.S.O. SS. Antonio e Biagio e C.Arrigo di Alessandria

    Alessandria, 15121, Italy

  • AOU Ospedale Careggi

    Florence, 50134, Italy

  • ASST-Papa Giovanni XXIII

    Bergamo, 24127, Italy

  • ASST-Spedali Civili

    Brescia, 25123, Italy

  • Azienda Ospedaliero Universitaria Maggiore della Carità

    Novara, 28100, Italy

  • FEA Hematología Hospital Universitario de Móstoles

    Madrid, Spain

  • Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

    Milan, 20122, Italy

  • Guy's and St. Thomas' NHS Foundation Trust.

    London, United Kingdom

  • Hopital Saint-Louis

    Paris, France

  • Hospital 12 de octubre

    Madrid, Spain

  • Hospital Clínic De Barcelona

    Barcelona, Barcellona, Spain

  • Hospital Clínico San Carlos

    Madrid, Spain

  • Hospital Clínico Universitario

    Valencia, Spain

  • Hospital General de Elche

    Alicante, Spain

  • Hospital General de La Palma

    Breña Alta, Santa Cruz De Tenerife, Spain

  • Hospital Gregorio Marañón

    Madrid, Spain

  • Hospital Moncloa

    Madrid, Spain

  • Hospital Ramón y Cajal

    Madrid, Spain

  • Hospital Universitario Infanta Leonor

    Madrid, Spain

  • Hospital Universitario La Paz

    Madrid, Spain

  • Hospital Universitario Príncipe de Asturias

    Alcalá de Henares, Madrid, Spain

  • Hospital Universitario de Burgos

    Burgos, Spain

  • Hospital Vall d'Hebron

    Barcelona, Spain

  • Hospital del Mar

    Barcelona, Barcellona, Spain

  • ICO Girona Hospital Josep Trueta Servei d'hematologia

    Girona, Spain

  • ICO L'Hospitalet - Hospital Moisès Broggi

    Sant Joan Despí, Barcelona, Spain

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy

  • IRCCS Policlinico San Matteo

    Pavia, 27100, Italy

  • Institut Català d' Oncologia - Hospital Germans Trias i Pujol

    Badalona, Barcelona, Spain

  • National Specialised Hospital for Active Treatment of Hematological Diseases

    Sofia, Bulgaria

  • New York-Presbyterian/Weill Cornell Medical Center

    New York, New York, 10065, United States

  • Ospedale Policlinico "G.B. Rossi" Borgo Roma

    Verona, 37134, Italy

  • Ospedale San Bortolo

    Vicenza, 36100, Italy

  • Ospedale San Gerardo di Monza

    Monza, Monza Brianza, 20900, Italy

  • Policlinico S.Orsola-Malpighi

    Bologna, 40138, Italy

  • Policlinico Universitario Fondazione Agostino Gemelli

    Roma, 00168, Italy

  • Servicio de Hematología Hospital General Universitario de Albacete

    Albacete, Spain

  • Sobas Wroclaw Medical University ·

    Wroclaw, Poland

  • University Clinic for Hematology, Oncology, Hemostaseology and Palliative Care, Johannes Wesling Medical Center

    Minden, Germany

  • University Hospital Halle, Department of Hematology/Oncology

    Halle, Saale, 06112, Germany

  • University Medical Center RWTH

    Aachen, Germany

  • University Medicine Greifswald - Hematology, Oncology, Stem Cell Transplantation and Palliative Care

    Greifswald, 17475, Germany

  • University hospital Dubrava-School of Medicine University of Zagreb

    Zagreb, Croatia