Probiotic tablet may rival mouthwash for fighting gum bacteria in diabetics
NCT ID NCT07489924
First seen Apr 03, 2026 · Last updated Jun 20, 2026 · Updated 10 times
Summary
This study tests whether a probiotic tablet (Lactobacillus reuteri Prodentis) works as well as a chlorhexidine mouthwash for reducing harmful bacteria in people with gum disease and type 2 diabetes. Twenty participants will use either the mouthwash or the probiotic for 30 days. Researchers will measure changes in Porphyromonas gingivalis bacteria levels to see if the probiotic is a good alternative.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Colima
Colima, 28040, Mexico
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Chlorhexidine mouthwash and probiotic (Lactobacillus reuteri Prodentis) tablet
What this could lead to
If it works, this could show that a simple probiotic tablet is as good as a mouthwash for controlling gum-disease bacteria in people with diabetes.
What could go wrong
This is a very small, early-phase trial with only 20 participants, so results may not apply to everyone. It only measures bacteria levels, not actual gum health or diabetes control.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.