New mouthwash could fight gum disease without staining teeth

NCT ID NCT07088666

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a new mouthwash called MicroRepair ABX works as well as the standard chlorhexidine mouthwash for treating plaque-induced gingivitis (gum inflammation). Forty adults with gum disease used one of the two mouthwashes twice daily for 14 days after a professional cleaning. The goal was to see if MicroRepair ABX could reduce gum pocket depth and plaque with fewer side effects like tooth staining or taste changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MicroRepair ABX mouthwash (zinc-hydroxyapatite microcrystals with antibacterial agents)
What this could lead to
If it works, this could offer a gentler alternative to standard mouthwash for managing gum inflammation, with less tooth staining and taste changes.
What could go wrong
This is a small, short-term study with only 40 participants, so results may not apply widely. It also does not test long-term safety or effectiveness.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

    Pavia, Lombardy, 27100, Italy

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