Mouthrinse showdown: which rinse heals gum grafts best?

NCT ID NCT07689695

Completed Symptom relief Sponsor: Yuzuncu Yil University Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests three mouthrinses—hypochlorous acid, hyaluronic acid, and chlorhexidine—to see which helps the palate heal best after a gum graft. Fifty-four adults having gum graft surgery will rinse with one of the three solutions for 14 days. Researchers will check wound healing, pain, and bleeding over 28 days to find the most effective rinse for recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hypochlorous acid, hyaluronic acid, and chlorhexidine mouthrinses
What this could lead to: If one mouthrinse proves superior, it could improve healing and reduce pain after gum graft surgery, making recovery more comfortable.
What could go wrong: This is a small, early-stage trial (54 participants) comparing existing products, so results may not apply to everyone. Any mouthrinse might cause irritation or not speed healing as hoped.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PALATAL DONOR SITE WOUND HEALING PERIODONTAL PLASTIC SURGERY

Contacts and locations

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Locations

Van Yuzuncu Yil University Faculty of Dentistry

Van, Tuşba, 65100, Turkey (Türkiye)

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