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Ancient resin meets modern surgery: could frankincense soothe gum graft wounds?

NCT ID NCT07772011

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial tests whether a gel made from frankincense, a natural resin, can improve healing of the palate after gum graft surgery. About 28 adults needing a gum graft will be randomly assigned to receive either the frankincense gel plus a protective stent, or the stent alone. Over 30 days, researchers will measure pain, wound closure, and patient satisfaction to see if the gel offers extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A topical gel made from frankincense (Boswellia serrata) applied to the wound after gum graft surgery.
What this could lead to
If it works, frankincense gel could become a simple, natural way to speed healing and reduce pain after gum graft procedures.
What could go wrong
This is a small, early-stage trial, so results may not apply widely. Frankincense can cause allergic reactions in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years. * Patients scheduled for a free gingival graft or connective tissue graft requiring a palatal donor site. * ASA physical status I-II Exclusion Criteria: * Known allergy or hypersensitivity to frankincense, Boswellia species, or frankincense formulation excipients. * Current smoker or tobacco user. * Uncontrolled systemic disease, such as uncontrolled diabetes mellitus. * Pregnant or lactating females

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Palatal donor site wound healing

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    Cairo, Cairo Governorate, Egypt

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