1,500 volunteers tracked to uncover hidden throat cancer clues

NCT ID NCT03644563

Ongoing Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is screening 1,500 adults for oral HPV infection and antibodies to build a group at higher risk for HPV-related throat cancer. Researchers will follow them over time to see which infections persist and what factors (like mouth bacteria or immune response) increase cancer risk. No treatment is given—the goal is to learn how to predict and possibly prevent this cancer in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify who is at highest risk for HPV-related throat cancer, leading to better screening or prevention strategies.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to any direct medical benefit, and results may take years to translate into practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

human papilloma virus infection oropharyngeal carcinoma oropharynx cancer Persistent Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HUMAN PAPILLOMA VIRUS OROPHARYNGEAL CANCER

Contacts and locations

Locations

Johns Hopkins Hospital

Baltimore, Maryland, 21205, United States

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