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Brain training without drugs: can imagining movement ease MS pain?

NCT ID NCT07710742

Symptom relief Sponsor: Uludag University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests two types of brain training—motor imagery (mentally picturing movements) and sensorimotor training (repetitive sensory exercises)—against standard therapy for people with multiple sclerosis who have neuropathic pain in their legs. The goal is to see which approach better reduces pain, improves balance, and speeds up reaction time. Participants will train twice a week for eight weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
motor imagery and sensorimotor training
What this could lead to
If effective, these brain-training methods could offer drug-free ways to reduce neuropathic pain and improve movement in people with MS.
What could go wrong
This is a small, early-stage study with no blinding, so results may not be conclusive or generalizable. The benefits may be modest or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 51 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-45 years of age, * Having received a definitive MS diagnosis according to the 2024 McDonald criteria, * Not having had a relapse in the past 3 months, * Having an EDSS score of ≤ 6.00, * Presence of neuropathic pain in the lower extremities that has persisted for at least 3 months or is recurrent, * Confirmation of the presence of neuropathic pain by a neurologist, Exclusion Criteria: * The presence of any other orthopedic or neurological condition that could interfere with participation in the study, * A level of spasticity in the lower extremities of ≥ 1+ on the Modified Ashworth Scale, * The presence of any hearing, vision, or cognitive impairment that could interfere with the assessments, * Receiving additional treatment beyond routine medication, * Participating in another physical therapy program during the study period, * Having conditions unrelated to MS that cause pain.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bursa Uludag University

    Bursa, Nilüfer, 16059, Turkey (Türkiye)

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