Finding the sweet spot: safer morphine dosing for hip surgery pain
NCT ID NCT06878014
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares different doses of morphine given with spinal anesthesia during total hip replacement. The goal is to find a dose that provides good pain relief for up to 24 hours while minimizing side effects like breathing problems, nausea, and itching. About 120 adults undergoing hip replacement will take part, and their pain levels and side effects will be tracked for 48 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
morphine (given into the spinal fluid)
What this could lead to
If successful, this could help doctors choose the safest and most effective dose of spinal morphine for hip replacement pain, reducing serious side effects like breathing trouble.
What could go wrong
This is a small, early-phase trial (120 people) focused on dosing, not a new treatment. Results may not apply to all patients, and morphine still carries risks like nausea, itching, and rare breathing depression.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Uniwersytecki Szpital Kliniczny nr 1 im. prof. Tadeusza Sokołowskiego PUM w Szczecinie
NOT_YET_RECRUITINGSzczecin, West Pomeranian Voivodeship, 70-204, Poland
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Wojewódzki Szpital Specjalistyczny nr 5 im. św. Barbary
RECRUITINGSosnowiec, Silesian Voivodeship, 41-214, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Zespół Opieki Zdrowotnej w Końskich
RECRUITINGGmina Końskie, Świętokrzyskie Voivodeship, 26-200, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact