New scan could help predict chemotherapy success in breast cancer

NCT ID NCT04332588

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a special PET/MRI scan using an investigational tracer called [18F]FMISO can help monitor how well chemotherapy works in people with HER2-positive breast cancer. The study involves 25 patients and is for imaging purposes only—it will not change their current treatment plan. The goal is to help doctors better understand and predict treatment response in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]FMISO (a radioactive tracer used for PET imaging)

What this could lead to

If successful, this could give doctors a better way to see early on whether chemotherapy is working for HER2+ breast cancer, potentially guiding more personalized treatment in the future.

What could go wrong

This is a very small, early-phase imaging study (25 participants) and is not designed to test a treatment. The results may not lead to changes in how patients are treated right now.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35249, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••