New flu vaccine manufacturing process put to the test

NCT ID NCT01773928

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a seasonal flu vaccine made with a modified manufacturing process in healthy adults aged 18 and older. The goal was to see if the new process produces a vaccine that works as well as the current version and is as safe as a licensed flu vaccine. About 1,928 participants received one of three vaccines, and researchers measured immune responses and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vero cell-derived trivalent seasonal influenza vaccine (modified manufacturing process)

What this could lead to

If successful, this could confirm that the modified manufacturing process produces a flu vaccine that is as effective and safe as current versions.

What could go wrong

This is a completed Phase 3 trial, but results may show the modified vaccine is not as effective or has more side effects than existing vaccines. The study also only included healthy adults, so findings may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anaheim Clinical Trials

    Anaheim, California, 92801, United States

  • Avail Clinical Research, LLC

    DeLand, Florida, 32720, United States

  • Benchmark Research

    Fort Worth, Texas, 76135, United States

  • Benchmark Research Austin

    Austin, Texas, 78705, United States

  • Benchmark Research San Francisco

    San Francisco, California, 94102, United States

  • California Research Foundation

    San Diego, California, 92103, United States

  • Center for Clinical Trials, LLC

    Paramount, California, 90723, United States

  • Clinical Research Atlanta

    Stockbridge, Georgia, 30281, United States

  • Clinical Research of South Florida

    Coral Gables, Florida, 33134, United States

  • East Valley Family Physicians, PLC

    Chandler, Arizona, 85224, United States

  • Heartland Research Associates, LLC

    Wichita, Kansas, 67207, United States

  • Jean Brown Research

    Salt Lake City, Utah, 84124, United States

  • Miami Research Associates

    South Miami, Florida, 33143, United States

  • PMG Research of Cary, LLC

    Cary, North Carolina, 27518, United States

  • Rapid Medical Research, Inc.

    Cleveland, Ohio, 44122, United States

  • Rochester Clinical Research Inc.

    Rochester, New York, 14609, United States

  • Spartanburg Medical Research

    Spartanburg, South Carolina, 29303, United States

  • Sundance Clinical Research, LLC

    St Louis, Missouri, 63141, United States

  • The Center for Pharmaceutical Research, P.C.

    Kansas City, Missouri, 64114, United States

  • Wake Research Associates, LLC

    Raleigh, North Carolina, 27612, United States