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App and brain zaps offer new hope for teen cancer survivors in pain

NCT ID NCT05746429

Symptom relief Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a mobile cognitive behavioral therapy (CBT) program, combined with a gentle brain stimulation technique called tDCS, could help teens who survived bone cancer manage chronic pain. Researchers first adapted the program for Black and Hispanic teens, then tested it in about 30 survivors. The goal was to see if the approach was feasible and could reduce pain intensity, interference, and related symptoms like anxiety and depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

68 people

The number who actually took part.

Started

Apr 2023

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusions Criteria for cultural adaption * Adult * Hispanic or non-Hispanic Black childhood cancer survivor or parent of Hispanic or non-Hispanic Black childhood cancer survivor * 18 years or older * Adolescents * 10-17 years-old survivors of childhood cancer * At least one year post treatment * Hispanic or non-Hispanic Black * Phase 4 only: History of chronic pain (i.e. pain that was present for more than 3 months) Exclusion Criteria for cultural adaptation * Adults/Adolescents * Inability or unwillingness of research participants or legal guardian/representative to give written informed consent Inclusion Criteria for feasibility study * Hispanic, non-Hispanic Black and non-Hispanic White 10-17-year-old survivors of pediatric cancer * At least one year post treatment * Pain present over the past 3 months and pain at least once per week * Pain interfering with at least one area of daily functioning Exclusion Criteria for feasibility study * Limb amputation * History of seizures or other neurological disorders * Implanted medical device or metal in the head * Serious comorbid psychiatric condition * Current substance abuse * History of development delay or significant cognitive impairment * History of brain tumor diagnosis

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Conditions

The condition(s) this trial relates to.

bone cancer bone sarcoma childhood malignant neoplasm chronic pain syndrome neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone sarcoma Childhood cancer

Contacts and locations

Locations

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

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