Liver function may affect prostate cancer drug levels

NCT ID NCT06860243

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study looked at how the experimental prostate cancer drug opevesostat (MK-5684) moves through the body in men with moderate liver impairment compared to healthy men. Sixteen male participants received a single dose, and researchers measured drug levels over time. The goal was to understand if liver problems change how the drug is processed, which helps guide safe dosing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY PARTICIPANTS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Clinical Pharmacology of Miami ( Site 0002)

    Miami, Florida, 33172, United States

  • Texas Liver Institute ( Site 0001)

    San Antonio, Texas, 78215, United States

Conditions

Explore the condition pages connected to this study.