Liver function may change how prostate drug works

NCT ID NCT06860243

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 22 times

Summary

This study looked at how the experimental prostate cancer drug opevesostat moves through the body in men with moderate liver impairment compared to healthy men. Sixteen male participants received a single dose, and researchers measured drug levels over time. The goal was to understand if liver problems affect drug processing, not to treat the disease.

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Contacts and locations

Locations

  • Clinical Pharmacology of Miami ( Site 0002)

    Miami, Florida, 33172, United States

  • Texas Liver Institute ( Site 0001)

    San Antonio, Texas, 78215, United States

Conditions

Explore the condition pages connected to this study.