Liver function may change how prostate cancer drug works

NCT ID NCT06860243

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how the experimental prostate cancer drug opevesostat moves through the body in men with moderate liver impairment compared to healthy men. Sixteen male participants received a single dose, and researchers measured drug levels over time. The goal was to understand if liver problems affect how the drug is processed, which helps guide future dosing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Pharmacology of Miami ( Site 0002)

    Miami, Florida, 33172, United States

  • Texas Liver Institute ( Site 0001)

    San Antonio, Texas, 78215, United States

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Other studies related to the condition(s) this trial covers.