New weekly shot could help control bleeding in hemophilia a

NCT ID NCT04204408

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medicine called Mim8 for people with hemophilia A, a condition where blood doesn't clot properly. Mim8 is given as a shot under the skin to help prevent bleeding episodes. The trial included 275 healthy volunteers and people with hemophilia A, with or without inhibitors, and lasted up to 44 months. Results focused on safety and how well the drug works to control bleeding.

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Conditions

The condition(s) this trial relates to.

hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HAEMOPHILIA A WITH OR WITHOUT INHIBITORS HEALTHY VOLUNTEERS

Contacts and locations

Locations

Arizona H&T Phoenix Child Hosp

Phoenix, Arizona, 85016-7710, United States
Charité - Campus Charité Mitte - Charité Research Organisation GmbH

Berlin, 10117, Germany
Charlotte Maxeke Johannesburg Academic Hospital

Parktown, Johannesburg, Gauteng, 2193, South Africa
Children's Healthcare Atlanta

Atlanta, Georgia, 30322, United States
Children's Hospital Los Angeles - Endocrinology

Los Angeles, California, 90027, United States
Children's Hospital of Michigan

Detroit, Michigan, 48201, United States
Cincinnati Child's Hsp Med Ctr

Cincinnati, Ohio, 45229, United States
Dayton Children Hemostati Ctr

Dayton, Ohio, 45404, United States
Ege Üniversitesi Hastanesi- Hematoloji

Izmir, 35100, Turkey (Türkiye)
Hacettepe Üniversitesi Hastanesi- Endokrinoloji

Ankara, 06230, Turkey (Türkiye)
Hospital La Fe - Hemostasia y Trombosis

Valencia, 46026, Spain
Hospital Regional Universitario de Málaga

Málaga, 29010, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Instytut Hematologii i Transfuzjologii

Warsaw, Masovian Voivodeship, 02-776, Poland
Istituto di Medicina Int. A. Bianchi Bonomi Univ. Milano

Milan, MI, 20124, Italy
Michigan State University

East Lansing, Michigan, 48823, United States
Nagoya University Hospital_Blood Transfusion

Aichi, 466-8560, Japan
Nara Medical University Hospital_Pediatrics

Nara, 634-8522, Japan
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Oxford Haemophilia Comprehensive Care Center

Oxford, OX3 7LJ, United Kingdom
Penn State MS Hershey Med Ctr

Hershey, Pennsylvania, 17033-2360, United States
Pietersburg Hospital

Polokwane, Limpopo, 0699, South Africa
Policlinico Umberto I Sezione Ematologia

Roma, 00161, Italy
Royal Free Haemophilia Comprehensive Care Centre

London, NW3 2QG, United Kingdom
Rush University Med. Cntr

Chicago, Illinois, 60612, United States
St. Jude Clinic Novant Health

Charlotte, North Carolina, 28204, United States
Szpital Uniwersytecki, Oddzial Kliniczny Hematologii

Krakow, 30-688, Poland
Tokyo Medical Univ. Hospital_Laboratory Medicine

Tokyo, 160-0023, Japan
Trakya Üniversitesi Tıp Fakültesi Hastanesi- Kardiyoloji

Edirne, 22030, Turkey (Türkiye)
UMHAT Tsaritsa Yoanna - ISUL EAD, Pediatric clinical hematology and oncology

Sofia, 1527, Bulgaria
University Of Michigan

Ann Arbor, Michigan, 48109, United States
University of Iowa_Iowa City

Iowa City, Iowa, 52242, United States
Universitätsklinik für Hämatologie

Bern, 3010, Switzerland
Universitätsklinik für Innere Medizin V

Innsbruck, 6020, Austria
Universitätsklinik für Innere Medizin V

Innsbruck, A 6020, Austria
Universitätsspital Zürich - Klinik für Medizinische Onkologie und Hämatologie

Zurich, 8091, Switzerland
Uniwersytecki Szpital Kliniczny W Poznaniu

Poznan, Greater Poland Voivodeship, 60-569, Poland
Vanderbilt Hemostasis Thrombosis Clinic

Nashville, Tennessee, 37232, United States
Versiti, CCBD

Milwaukee, Wisconsin, 53226, United States
Vivantes Netzwerk für Gesundheit GmbH - Vivantes Klinikum im Friedrichshain

Berlin, 10249, Germany

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