New migraine pill aims to stop pain in 2 hours – major trial underway

NCT ID NCT07645924

Recruiting now Symptom relief Sponsor: Kallyope Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 11 times

Summary

This study tests a new drug, elismetrep, to see if it can quickly stop migraine pain and bothersome symptoms like nausea or light sensitivity. About 1800 adults with frequent migraines will receive either the drug or a placebo. The main goal is to measure how many people are pain-free within 2 hours of taking the medication.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

Locations

AMR Clinical - Kansas City
RECRUITING

Kansas City, Missouri, 64114, United States
AMR Clinical - Las Vegas
RECRUITING

Las Vegas, Nevada, 89119, United States
AMR Clinical - Lexington
RECRUITING

Lexington, Kentucky, 40509, United States
AMR Clinical - Norfolk
RECRUITING

Norfolk, Virginia, 23502, United States
AMR Mobile
RECRUITING

Mobile, Alabama, 36608, United States
APD Clinical Research
RECRUITING

Cypress, Texas, 77372, United States
Access Clinical Trials, Inc
RECRUITING

Nashville, Tennessee, 37203, United States
Acclaim Clinical Research
RECRUITING

San Diego, California, 92120, United States
Advanced Neurosciences Research
RECRUITING

Fort Collins, Colorado, 80528, United States
Advanced Research Institute
RECRUITING

Ogden, Utah, 84405, United States
Advanced Research Institute - Portland
RECRUITING

Portland, Oregon, 97223, United States
Advanced Research Institute - Reno
RECRUITING

Reno, Nevada, 89511, United States
Aim Trials, LLC
RECRUITING

Plano, Texas, 75093, United States
Albuquerque Clinical Trials
RECRUITING

Albuquerque, New Mexico, 87102, United States
Arkansas Clinical Research
RECRUITING

Little Rock, Arkansas, 72205, United States
Artemis Institute for Clinical Research
RECRUITING

Riverside, California, 92503, United States
Axiom Research, LLC
RECRUITING

Colton, California, 92324, United States
Axiom Research, Orange County
RECRUITING

Irvine, California, 92604, United States
Boston Clinical Trials - Alcanza
RECRUITING

Boston, Massachusetts, 02131, United States
CTI Clinical Research Center
RECRUITING

Lexington, Kentucky, 45212, United States
Carolina Research Center, Inc
RECRUITING

Shelby, North Carolina, 28150, United States
Cedar Crosse Research Center
RECRUITING

Chicago, Illinois, 60607, United States
CenExel Sherman Oaks CA (California Neuroscience Research)
RECRUITING

Sherman Oaks, California, 91403, United States
Central New York Clinical Research
NOT_YET_RECRUITING

Manlius, New York, 13104, United States
Central Research Associates, LLC (CRA) dba Flourish Research
RECRUITING

Birmingham, Alabama, 35205, United States
Chase Medical Research, LLC
RECRUITING

Waterbury, Connecticut, 06708, United States
Chicago Headache Center & Research Institute
NOT_YET_RECRUITING

Chicago, Illinois, 60657, United States
Chicago Headache Center & Research Institute
NOT_YET_RECRUITING

Naperville, Illinois, 60563, United States
CincyScience
RECRUITING

West Chester, Ohio, 45069, United States
Clinical Associates Midwest, LLC
RECRUITING

Overland Park, Kansas, 66214, United States
Clinical Investigation Specialists, Inc.
RECRUITING

Kenosha, Wisconsin, 53144, United States
Clinical Research Associates, Inc.
RECRUITING

Nashville, Tennessee, 37203, United States
Clinical Research Institute
RECRUITING

Minneapolis, Minnesota, 55402, United States
Clinical Research Institute
RECRUITING

Los Angeles, California, 90048, United States
Clinical Research Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19114, United States
Clinpoint Trials
RECRUITING

Waxahachie, Texas, 75165, United States
Clinvest Headlands LLC
RECRUITING

Springfield, Missouri, 65807, United States
Coastal Carolina Research Center
RECRUITING

North Charleston, South Carolina, 29405, United States
Collective Medical Research
RECRUITING

Overland Park, Kansas, 66212, United States
Crescent City Headache & Neurology Center
RECRUITING

Chalmette, Louisiana, 70043, United States
DM Clinical Research
RECRUITING

Houston, Texas, 77081, United States
DelRicht Research
RECRUITING

Gulfport, Mississippi, 39503, United States
DelRicht Research
RECRUITING

Tulsa, Oklahoma, 74133, United States
DelRicht Research
RECRUITING

Atlanta, Georgia, 30329, United States
DelRicht Research
RECRUITING

New Orleans, Louisiana, 70115, United States
Dent Neuro Institute, Buffalo
RECRUITING

Amherst, New York, 14226, United States
Diablo Clinical Research
RECRUITING

Walnut Creek, California, 94598, United States
Downtown L.A. Research Center, Inc.
RECRUITING

Los Angeles, California, 90017, United States
Drug Studies America
RECRUITING

Marietta, Georgia, 30060, United States
Empire Clinical Research
RECRUITING

Pomona, California, 91767, United States
Encompass Clinical Research
RECRUITING

Spring Valley, California, 91978, United States
Excel Clinical Research
NOT_YET_RECRUITING

Las Vegas, Nevada, 89109, United States
Excell Research
RECRUITING

Oceanside, California, 92056, United States
Eximia Research - NC, LLC
RECRUITING

Raleigh, North Carolina, 27607, United States
Fieve Clinical Research, Inc
RECRUITING

New York, New York, 10017, United States
Focus Clinical Research
RECRUITING

West Hills, California, 91307, United States
Frontier Clinical Research
RECRUITING

Morgantown, West Virginia, 26505, United States
Frontier Clinical Research, LLC
RECRUITING

Scottdale, Pennsylvania, 15683, United States
Frontier Clinical Research, LLC
RECRUITING

Smithfield, Pennsylvania, 15478, United States
FutureSearch Trials of Dallas, LP
RECRUITING

Dallas, Texas, 75251, United States
FutureSearch Trials of Neurology
RECRUITING

Austin, Texas, 78731, United States
GMG Clinical Research, LLC dba Radiance Clinical Research
RECRUITING

Lampasas, Texas, 76550, United States
Granger Medical Clinic
RECRUITING

Riverton, Utah, 84096, United States
Guildford Neurologic Research Partners, LLC
RECRUITING

Greensboro, North Carolina, 27405, United States
Headache Wellness Center
RECRUITING

Greensboro, North Carolina, 27405, United States
Headlands Research - PharmaSite
RECRUITING

Pikesville, Maryland, 21208, United States
Health Research of Hampton Roads, Inc. (HRHR)
RECRUITING

Newport News, Virginia, 23606, United States
Healthcare Research Network
RECRUITING

Hazelwood, Missouri, 63042, United States
Healthcare Research Network II, LLC
RECRUITING

Flossmoor, Illinois, 60477, United States
Heartland Research Associates, LLC - An AMR Company
RECRUITING

Wichita, Kansas, 67207, United States
Hightower Clinical
RECRUITING

Oklahoma City, Oklahoma, 73102, United States
Hometown Research
RECRUITING

Columbus, Ohio, 43228, United States
Hometown Research
RECRUITING

Milford, Ohio, 45150, United States
Horizon Clinical Research and Gill Neuroscience
RECRUITING

Cypress, Texas, 77429, United States
IMA Clinical Research - Las Vegas
RECRUITING

Las Vegas, Nevada, 89102, United States
IMMUNOe Research Centers
RECRUITING

Centennial, Colorado, 80112, United States
Integrated Clinical Trials Solution
NOT_YET_RECRUITING

West Des Moines, Iowa, 50265, United States
J. Lewis Research, Inc. / Foothill Family Clinic
RECRUITING

Salt Lake City, Utah, 84109, United States
J. Lewis Research, Inc. / Foothill Family Clinic
RECRUITING

Salt Lake City, Utah, 84121, United States
J. Lewis Research, Inc. / Foothill Family Clinic Draper
RECRUITING

Draper, Utah, 84020, United States
Kinetic Clinical Research
RECRUITING

West Covina, California, 91790, United States
Las Vegas Clinical Trials
RECRUITING

North Las Vegas, Nevada, 89030, United States
Leading Edge Research LA, LLC
RECRUITING

Encino, California, 91316, United States
Lehigh Center for Clinical Research
RECRUITING

Allentown, Pennsylvania, 18103, United States
M3 Wake Research - Mission Mental Health (WR-MMH)
RECRUITING

Mission Viejo, California, 92691, United States
MCB Clinical Research Centers
RECRUITING

Colorado Springs, Colorado, 80910, United States
MedVadis Research Corporation, LLC
RECRUITING

Waltham, Massachusetts, 02451, United States
Michigan Headache Pain & Neurological Institute
RECRUITING

Ann Arbor, Michigan, 48104, United States
Monroe Biomedical Research (former L-MARC Research Center)
NOT_YET_RECRUITING

Louisville, Kentucky, 40213, United States
OK Clinical Research, LLC
RECRUITING

Edmond, Oklahoma, 73034, United States
OnSite Clinical Solutions
RECRUITING

Charlotte, North Carolina, 28277, United States
Pantheon Clinical Research
RECRUITING

Bountiful, Utah, 84010, United States
Physicians to Children & Adolescents, PSC (Kentucky Pediatric / Adult Research)
RECRUITING

Bardstown, Kentucky, 40004, United States
Preferred Primary Care Physicians, Inc.
RECRUITING

Pittsburgh, Pennsylvania, 15236, United States
ProScience Research Group
RECRUITING

Culver City, California, 90230, United States
Proven Endpoints
RECRUITING

Ridgeland, Mississippi, 39157, United States
Redbird Research
RECRUITING

Las Vegas, Nevada, 89119, United States
Rochester Clinical Research
RECRUITING

Rochester, New York, 14609, United States
SPRI Clinical Trials, LLC
RECRUITING

Brooklyn, New York, 11235, United States
Seattle Clinical Research Center
RECRUITING

Seattle, Washington, 98104, United States
Sleep Care Research Institute d/b/a Clinical Research Atlanta-Stockbridge
RECRUITING

Stockbridge, Georgia, 30281, United States
StudyMetrix Research
RECRUITING

City of Saint Peters, Missouri, 63303, United States
Summit Research Network
RECRUITING

Portland, Oregon, 97210, United States
Sundance Clinical Research
RECRUITING

St Louis, Missouri, 63141, United States
Sunwise Clinical Research
RECRUITING

Walnut Creek, California, 94596, United States
Tekton Research
RECRUITING

Austin, Texas, 78745, United States
Tekton Research, Inc.
RECRUITING

Yukon, Oklahoma, 73099, United States
The Neurology Group
RECRUITING

Pomona, California, 91767, United States
TrialSphere
RECRUITING

Chandler, Arizona, 85286, United States
True North Neurology
RECRUITING

Commack, New York, 11725, United States
Upstate Clinical Research Associates
RECRUITING

Williamsville, New York, 14221, United States
Victorium Clinical Research
RECRUITING

Houston, Texas, 77024, United States
WR-ClinSearch, LLC
RECRUITING

Chattanooga, Tennessee, 37421, United States
Wake Research Las Vegas Rainbow
RECRUITING

Las Vegas, Nevada, 89118, United States

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