New registry aims to sharpen liver tumor ablation techniques

NCT ID NCT04107766

Terminated Knowledge-focused Sponsor: Ethicon, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracked over 1,200 people with liver cancer who received microwave ablation, a procedure that uses heat to destroy tumors. Researchers collected data over 5 years to see how well the ablation worked and how long patients lived. The goal was to create better guidelines for using this technique in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Microwave ablation (device procedure)
What this could lead to: If successful, this registry could provide doctors with better guidelines for using microwave ablation to treat liver tumors, potentially improving outcomes.
What could go wrong: This was an observational study, not a controlled trial, so it cannot prove that the ablation technique itself improves survival. The study was also terminated early, which may limit the data collected.

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Conditions

The condition(s) this trial relates to.

carcinoma of liver and intrahepatic biliary tract liver and intrahepatic bile duct neoplasm liver cancer Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER OF THE LIVER LIVER CANCER NEOPLASMS, LIVER

Contacts and locations

Locations

Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
David Geffen School of Medicine at UCLA

Los Angeles, California, 90095, United States
Hôpital Européen Georges-Pompidou

Paris, 75015, France
ICAHN School of Medicine at Mount Sinai

New York, New York, 10029, United States
Loma Linda University Medical Center

Loma Linda, California, 92354, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Norfolk and Norwich University Hospital

Norwich, NR4 7UY, United Kingdom
Olive View UCLA

Sylmar, California, 91342, United States
Radboud UMC

Nijmegen, 6525 GA, Netherlands
Renji Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, 200120, China
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
Seoul National University Bundang Hospital (SNUBH)

Seongnam-si, Gyeonggi-do 13620, South Korea
Singapore General Hospital

Singapore, 168582, Singapore
St. James's University Hospital

Leeds, LS9 7TF, United Kingdom
Sutter Institute for Medical Research

Sacramento, California, 95816, United States
Tan Tock Seng Hospital

Singapore, 308433, Singapore
Tenon Hospital

Paris, 75020, France
The First Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, 510000, China
The Royal Marsden Hospital

London, SW3 6JJ, United Kingdom
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
University Hospital Regensburg

Regensburg, 93053, Germany
University Medical Center Goningen

Groningen, 9713 GZ, Netherlands
University of Virginia

Charlottesville, Virginia, 22908, United States
University of Washington Medical Center

Seattle, Washington, 98101, United States
University of Wisconsin At Madison

Madison, Wisconsin, 53792, United States
VUMC Amsterdam

Amsterdam, 1081 HV, Netherlands

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