New supplement trial aims to fight chemo fatigue in breast cancer patients

NCT ID NCT06137833

Recruiting now Symptom relief Sponsor: Pharmanutra S.p.a. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily supplement called APPORTAL® can reduce fatigue in breast cancer patients undergoing chemotherapy. The supplement contains a mix of vitamins, minerals, and other nutrients. 92 women will take either the supplement or a placebo for 8 weeks, alongside standard exercise recommendations. Researchers will measure changes in fatigue, muscle strength, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: APPORTAL® (a dietary supplement containing vitamins, minerals, L-arginine, L-carnitine, coenzyme Q10, and other nutrients)
What this could lead to: If it works, this could offer a safe, non-drug way to reduce fatigue and improve quality of life for breast cancer patients during chemotherapy.
What could go wrong: This is a small, early-stage trial (92 people) testing a supplement, not a drug. The placebo effect is common in fatigue studies, and results may not apply to all cancer types or treatments.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER FATIGUE

Contacts and locations

Locations

Cancer Center U.O. Oncologia Medica ed Ematologia IRCCS Humanitas Research Hospital
RECRUITING

Rozzano, MILANO, 20089, Italy
Dipartimento di Oncologia Azienda Sanitaria Universitaria Integrata di Udine
RECRUITING

Udine, UDINE, 33100, Italy
U.O. Oncologia 2 Universitaria A.O.U. Pisana
RECRUITING

Pisa, PISA, 56126, Italy
U.O.C. Oncologia medica ASST Spedali Civili di Brescia
RECRUITING

Brescia, BRESCIA, 25123, Italy
UOSD di Medicina di Precisione e Senologia, Policlinico Universitario A. Gemelli
RECRUITING

Rome, ROME, 00168, Italy

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