Could a daily supplement soothe dry eyes?

NCT ID NCT07453212

ENROLLING_BY_INVITATION Symptom relief Sponsor: Varol TUNALI Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests whether an oral supplement that targets gut bacteria can improve dry eye symptoms in adults with moderate evaporative dry eye disease. Over 8 weeks, 130 participants will take either the supplement or a placebo. The main goal is to see if symptoms, measured by a standard questionnaire, improve more with the supplement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: microbiome-targeted oral food supplement
What this could lead to: If it works, this could offer a simple, non-invasive way to ease dry eye symptoms by targeting gut health.
What could go wrong: This is an early-stage trial with only 130 participants, so results may not apply to everyone. The supplement may not work better than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome Meibomian Gland Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE EVAPORATIVE DRY EYE DISEASE MEIBOMIAN GLAND DYSFUNCTION (DISORDER)

Contacts and locations

Locations

Istinye University

Istanbul, Turkey (Türkiye)
Medipol University

Istanbul, Turkey (Türkiye)
T.C. İstanbul Prof. Dr. Cemil Taşcıoğlu Şehir Hastanesi

Istanbul, 34384, Turkey (Türkiye)

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