Can pond scum become a protein powerhouse? a trial tests microalgae drinks

NCT ID NCT07791420

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First seen Aug 28, 2026 · Last updated Sep 02, 2026 · Updated 2 times

Summary

Researchers at the National University of Singapore are testing how different protein sources change the body's metabolites. Healthy Chinese adults will drink shakes made from microalgae, whey, soy, or a placebo, and provide blood and urine samples. The study aims to see if processed microalgae offers a viable alternative to traditional proteins.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Microalgae protein drinks (bead-milled and non-bead-milled), compared with whey protein, soy protein, and a maltodextrin placebo
What this could lead to
If microalgae proteins digest and absorb well, they could become a sustainable plant-based protein source for everyday nutrition.
What could go wrong
This is a small, early metabolic study in healthy adults, so results may not apply to the general population or predict long-term health effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English-literate and able to give informed consent * Singaporean Chinese Adults aged 21 to 60 (inclusive) * Body mass index of 18.5 to 23.0 kg/m\^2 (inclusive) * Healthy (Based on results from screening session) Exclusion Criteria: * Currently participating in another clinical study that involves altering the regular diet and/or involves consuming a dietary supplement or investigated food product as an intervention * High blood pressure (≥ 140/90 mmHg) * Underlying health conditions that may affect metabolic functions * Consuming amino acid or protein supplements, or protein drinks, regularly (i.e., more than three times a week) for the past 3 months, and not willing to discontinue usage 3 months before and during the study duration * Weight change \> 3 kg in the past 3 months * Weight \< 50 kg * Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout) * Current smokers or have quit smoking for less than 5 years * Drinking \> 2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer/cider or 45 ml of distilled spirit) * If drinking ≤ 2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits * Not willing to stop consumption of caffeinated beverages 10 to 12 houFrs before and on the day of the test visits * Currently on a specialised diet (e.g., Halal, vegetarian, vegan, weight loss diet) * Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: seaweed or algae and their derived products, milk/dairy products (e.g., whey), starch/starch-derived products (e.g., rice, corn, wheat, potato), soy/soy-derived products, gluten, eggs, nuts, peanuts, fish and crustaceans * Disease or impairment of the kidney and/or liver\* * Currently diagnosed with diabetes\*, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and/or G6PD deficiency * Taking antibiotics 2 weeks prior to study participation * Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition * Poor peripheral venous access based on past experiences with blood drawing * Individuals with anemia and/or blood clotting disorders * Donated blood within the 12 weeks prior to study participation * Individuals with pacemaker or related electrical medical devices * Pregnant, lactating, or planning pregnancy in the next 6 months

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Contacts and locations

Locations

  • NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117550

    Singapore, Singapore

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