Common C-Section drug may be unnecessary, study finds

NCT ID NCT05033041

Completed Knowledge-focused Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether giving metoclopramide before a planned C-section actually lowers stomach fluid, which is meant to prevent rare but serious aspiration during anesthesia. Researchers compared stomach volumes using ultrasound in 72 healthy women who received either the drug or a placebo. The goal is to see if the drug offers real benefit or just adds side effects, which could change future anesthesia guidelines.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: metoclopramide
What this could lead to: If results show metoclopramide doesn't help, guidelines may change to avoid unnecessary side effects in women having planned C-sections.
What could go wrong: This is a small, completed Phase 4 study (72 people) that may not apply to all patients or emergency C-sections. It tests a common drug, not a new breakthrough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASPIRATION CESAREAN SECTION PREGNANCY

Contacts and locations

Locations

Northwestern Memorial Hospital and Prentice Women's Hospital

Chicago, Illinois, 60611, United States

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