Diabetes drug gel shows promise against gum disease in new trial

NCT ID NCT07215156

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a gel made from the diabetes drug metformin can improve gum healing better than a standard antimicrobial gel (chlorhexidine) when used alongside deep cleaning. Sixty adults with moderate gum disease will be split into three groups: cleaning alone, cleaning plus metformin gel, or cleaning plus chlorhexidine gel. The goal is to see which approach best reduces inflammation, deepens tissue attachment, and boosts bone density over six months.

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