Gum disease gel could save your teeth

NCT ID NCT07634341

Not yet recruiting Disease control Sponsor: Fayoum University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a gel made from doxycycline and atorvastatin in tiny chitosan particles, placed directly into gum pockets after standard deep cleaning. The goal is to reduce gum inflammation, pocket depth, and bone loss in 80 adults with moderate to severe chronic periodontitis. Researchers will measure gum health and bone levels over time to see if the gel improves outcomes compared to cleaning alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: doxycycline and atorvastatin loaded chitosan nanoparticles gel
What this could lead to: If it works, this could offer a more effective gum treatment that fights infection, reduces inflammation, and helps regrow bone.
What could go wrong: This is a small, early-phase trial with only 80 participants. The gel is new and may not work better than standard care. Risks include local irritation or no added benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PERIODONTITIS

Contacts and locations

Locations

Fayoum

Al Fayyum, Egypt

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