Can a common diabetes drug calm inflammation in drug users?

NCT ID NCT06829238

First seen Apr 30, 2026 · Last updated May 22, 2026 · Updated 3 times

Summary

This study tests whether metformin, a common diabetes drug, can lower inflammation and improve immune function in 100 adults aged 18-64 who have a history of injection drug use, with or without HIV. Participants will take metformin or a placebo for 16 weeks and have their immune systems checked, including how well they respond to vaccines. The goal is to see if metformin can help restore immune balance in this high-risk group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.