Gene test may predict metformin success in PCOS
NCT ID NCT05680805
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether certain gene variations influence how well the diabetes drug metformin works in women with polycystic ovary syndrome (PCOS). Researchers will give 100 women with PCOS metformin for 24 weeks and measure changes in insulin resistance, weight, and cholesterol. They will also check for specific gene variants to see if they predict who responds best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- metformin
- What this could lead to
- If successful, this could help doctors predict which PCOS patients will benefit most from metformin based on their genes.
- What could go wrong
- This is a small, early-phase study focused on genetic links, not a treatment trial. Results may not change clinical practice directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University
Dhaka, 1000, Bangladesh
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could interval training and fasting tame PCOS insulin resistance?
- New PCOS study aims to map hidden patterns of the condition
- New hope for PCOS: extended letrozole or adding inositol may help ovulation
- New hope for PCOS: supplement combo aims to restore ovulation
- Could a protein boost make a PCOS supplement work better?