Radical new schedule aims to cure High-Risk ewing sarcoma

NCT ID NCT07194044

Recruiting now ⭐️ CURE ⭐️ Sponsor: H. Lee Moffitt Cancer Center and Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests a new treatment schedule for people with metastatic Ewing sarcoma, a rare and aggressive cancer. The approach uses an intense first attack on cancer cells, followed by targeted strikes and long-term maintenance to wipe out remaining cells. The goal is a cure. The study is for patients over 1 year old who are healthy enough for the therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

CIC-rearranged sarcoma Ewing sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC EWING SARCOMA

Contacts and locations

Locations

Cleveland Clinic Children's
NOT_YET_RECRUITING

Cleveland, Ohio, 44195, United States
Connecticut Children's Medical Center
NOT_YET_RECRUITING

Hartford, Connecticut, 06106, United States
Helen DeVos Children's Hospital
NOT_YET_RECRUITING

Grand Rapids, Michigan, 49503, United States
Levine Cancer Institute
NOT_YET_RECRUITING

Charlotte, North Carolina, 28204, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States
Nemours Jacksonville
NOT_YET_RECRUITING

Jacksonville, Florida, 32207, United States
Phoenix Children's Hospital
RECRUITING

Phoenix, Arizona, 85016, United States
Primary Children's Hospital
RECRUITING

Salt Lake City, Utah, 84113, United States
Roswell Park Comprehensive Cancer Center
NOT_YET_RECRUITING

Buffalo, New York, 14263, United States
University of Alabama at Birmingham (Children's of Alabama)
RECRUITING

Birmingham, Alabama, 35233, United States
University of Florida
RECRUITING

Gainesville, Florida, 32610, United States
University of Kentucky
NOT_YET_RECRUITING

Lexington, Kentucky, 40536, United States
University of Miami
RECRUITING

Miami, Florida, 33136, United States
University of North Carolina
NOT_YET_RECRUITING

Chapel Hill, North Carolina, 27599, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.