Tiny study aims to unlock why weight loss gets harder
NCT ID NCT07128238
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why metabolism often slows down when people with obesity lose weight through diet and exercise. Ten participants will follow an 8-week lifestyle program while researchers measure changes in body composition, core temperature, and energy use. The goal is to understand what drives this 'metabolic adaptation' and find ways to improve weight loss success.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lifestyle intervention (diet and exercise)
- What this could lead to
- If successful, this study could reveal why metabolism slows during weight loss, potentially leading to better strategies for maintaining weight loss.
- What could go wrong
- This is a very small, early-stage study with only 10 participants, so findings may not apply broadly. It is observational in nature and does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI: ≥30kg/m2 Willing to participate in an 8-week weight-loss camp program Exclusion Criteria: * Metabolic or cardiovascular diseases (such as diabetes) Mental disorders (such as depression and claustrophobia) Infectious diseases (such as AIDS, tuberculosis, malaria) High blood pressure Pregnant, lactating, or prepare for pregnancy Implanted or portable electro-mechanical device Taking antihypertensive or weight-loss medications
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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