Tiny study aims to unlock why weight loss gets harder

NCT ID NCT07128238

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why metabolism often slows down when people with obesity lose weight through diet and exercise. Ten participants will follow an 8-week lifestyle program while researchers measure changes in body composition, core temperature, and energy use. The goal is to understand what drives this 'metabolic adaptation' and find ways to improve weight loss success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lifestyle intervention (diet and exercise)
What this could lead to
If successful, this study could reveal why metabolism slows during weight loss, potentially leading to better strategies for maintaining weight loss.
What could go wrong
This is a very small, early-stage study with only 10 participants, so findings may not apply broadly. It is observational in nature and does not test a new treatment.

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Conditions

The condition(s) this trial relates to.

Body Temperature Changes obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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