New drug MER511 enters first human trial for Graves' disease

NCT ID NCT07305818

Recruiting now Disease control Sponsor: Merida Biosciences Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 3 times

Summary

This early-stage trial tests a new biologic drug called MER511 in 100 adults with Graves' disease. The main goal is to check safety and side effects, and to see how the body handles the drug when given by IV or injection. Participants must be on stable thyroid medication. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MER511 (a biologic drug given by IV or injection under the skin)
What this could lead to: If successful, this could point toward a new treatment option for Graves' disease that helps control the condition with fewer side effects.
What could go wrong: This is a very early Phase 1 trial focused on safety, so it is not yet known if MER511 works. Side effects are possible, and the drug may not prove effective in later studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Graves disease hyperthyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRAVES' DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Site # 1101
RECRUITING

Hollywood, Florida, 33024, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1102
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1103
WITHDRAWN

Phoenix, Arizona, 85053, United States
Site # 1104
RECRUITING

Columbus, Ohio, 43203, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1105
RECRUITING

Webster, Texas, 77598, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1107
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1108
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1109
RECRUITING

Wesley Chapel, Florida, 33544, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Site # 1112
RECRUITING

Miami, Florida, 33125, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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