New hope for debilitating chronic cough? drug trial targets root cause

This study tested whether mepolizumab, an existing medication, could reduce the number of coughs in adults suffering from a long-term, hard-to-treat cough linked to specific airway inflammation. It involved 46 adults with chronic cough and evidence of eosinophilic airway disease, such as asthma or bronchitis. Participants received either the real drug or a placebo injection over 12 weeks to see if it lowered their measured cough frequency and improved their quality of life.