Scientists probe Hippocampus' role in directing eyes to build memories
NCT ID NCT05945628
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study investigates how the hippocampus, a brain region critical for memory, helps guide eye movements to form lasting memories. Researchers will record brain activity directly from the hippocampus in people with epilepsy who are already undergoing brain surgery, while they perform memory tasks. By also using mild electrical stimulation, the team aims to understand whether the hippocampus actively directs visual attention to create coherent memories. The findings could shed light on memory problems in neurological and psychiatric disorders.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could reveal how memory formation goes wrong in conditions like Alzheimer's or PTSD, pointing toward new therapies.
- What could go wrong
- This is a small, early-stage observational study in people with epilepsy, so findings may not apply to the general population. Direct clinical benefits are not guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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