Could a common Alzheimer's drug sharpen thinking in schizophrenia?

NCT ID NCT04857983

First seen Feb 13, 2026 · Last updated Apr 29, 2026 · Updated 12 times

Summary

This study looked at whether adding the drug memantine to a computer-based cognitive training program could improve thinking skills and daily function in people with schizophrenia or schizoaffective disorder. 62 adults took part in a double-blind trial where some received memantine and others a placebo alongside the training. The goal was to see if memantine could enhance the brain's ability to learn and lead to better real-world outcomes.

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Contacts and locations

Locations

  • Clinical Teaching Facility (CTF B-403 at UCSD Medical Center)

    San Diego, California, 92103, United States

Conditions

Explore the condition pages connected to this study.