Two-Drug combo shows promise against brain metastases in advanced melanoma

NCT ID NCT03873818

First seen Jan 10, 2026 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This study tested a combination of two immunotherapy drugs (low-dose ipilimumab and pembrolizumab) in 24 people with advanced melanoma that had spread to the brain. The goal was to see if the treatment could shrink or control the brain tumors and to check for side effects. Participants received the drugs intravenously, and the study measured how many had their cancer stop growing for at least six months.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.