Can a diabetes drug help prevent uterine cancer?
NCT ID NCT04576104
First seen Sep 30, 2025 · Last updated May 13, 2026 · Updated 25 times
Summary
This study looks at whether adding metformin (a diabetes drug) to standard hormone therapy (megestrol acetate) can better control uterine pre-cancer and stop it from becoming cancer. About 51 women with this pre-cancer condition will receive either the standard drug alone or the combination before their planned surgery. The goal is to see which approach reduces abnormal cell growth more effectively.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Northwestern Medicine Central DuPage Hospital
Winfield, Illinois, 60190, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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University of Colorado
Denver, Colorado, 80217-3364, United States
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University of Minnesota/Masonic Cancer Center
Minneapolis, Minnesota, 55455, United States
Conditions
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