Blueberry compound may boost cancer treatment in small trial

NCT ID NCT03671811

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests whether adding pterostilbene, an antioxidant found in blueberries, to the hormone drug megestrol acetate can better slow endometrial cancer growth before hysterectomy. About 44 patients will receive either megestrol acetate alone or with pterostilbene for a short time before surgery. The main goal is to see if the combination reduces tumor cell growth more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

megestrol acetate and pterostilbene

What this could lead to

If it works, this could point toward a way to shrink endometrial tumors before surgery, possibly improving outcomes.

What could go wrong

This is a small, early-phase trial with only 44 participants, so results may not apply widely. The added benefit of pterostilbene is uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atypical endometrial hyperplasia endometrial carcinoma Endometrial Hyperplasia endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States