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New gel boosts knee cartilage repair in older adults

NCT ID NCT06249828

Completed Disease control Sponsor: L&C Bio Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding MegaCarti® to standard microfracture surgery improves knee cartilage repair in people aged 50-65 with knee cartilage injuries. 61 participants received either microfracture alone or microfracture plus MegaCarti®. The main goal was to see if MRI scans at 48 weeks showed better cartilage regrowth with the added treatment.

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Conditions

The condition(s) this trial relates to.

Fractures, Stress osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

  • Ajou University Medical Center

    Gyeonggi-do, 16499, South Korea

  • Catholic Kwandong University International St.Mary's Hospital

    Incheon, South Korea

  • Chung-Ang University Gwangmyeong Hospital

    Gyeonggi-do, 14353, South Korea

  • Konkuk University Medical Center

    Seoul, 05030, South Korea

  • Yonsei Sarang Hospital

    Seoul, 06702, South Korea

  • Yonsei University College of Medicine, Gangnam Severance Hospital

    Seoul, 06273, South Korea

  • Yonsei University Health System, Severance Hospital

    Seoul, 03722, South Korea

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