Could a mediterranean diet and exercise ease Parkinson's by reshaping the gut?

NCT ID NCT07097103

Not yet recruiting Disease control Sponsor: IRCCS San Raffaele Roma Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This pilot study tests whether a Mediterranean diet and regular exercise can alter the gut microbiome in people with Parkinson's disease. Researchers will track changes in gut bacteria and look for links to symptom severity and quality of life. The study involves 80 participants aged 35–80 with mild to moderate Parkinson's.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mediterranean diet and physical exercise
What this could lead to: If it works, this could point toward a non-drug way to manage Parkinson's symptoms by targeting the gut microbiome.
What could go wrong: This is a small pilot study, so results may not apply to everyone. The diet and exercise plan requires commitment, and benefits may be modest or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE (PD)

Contacts and locations

Locations

Casa di Cura San Raffale Cassino

Cassino, Frosinone, 03043, Italy
IRCCS San Raffale Roma

Rome, Lazio, 00166, Italy

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