Can a Two-Drug combo beat single painkiller after stomach surgery?
NCT ID NCT07768514
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This trial tests whether a combination of acetaminophen and ibuprofen (Maxigesic) given through an IV can control pain better than acetaminophen alone after laparoscopic or robotic stomach cancer surgery. About 90 adults undergoing this surgery will be randomly assigned to one of the two treatments, and their pain levels will be tracked for 72 hours. The goal is to see if the combo reduces pain more effectively and safely, potentially lowering the need for stronger opioid painkillers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A fixed-dose combination of acetaminophen and ibuprofen, given intravenously as Maxigesic
- What this could lead to
- If effective, this could offer a better, opioid-sparing way to manage pain after gastric cancer surgery, potentially reducing opioid-related side effects.
- What could go wrong
- This is a small, phase 2 trial, so results may not apply broadly. The combination may not prove superior to acetaminophen alone, and there are risks like bleeding or kidney issues from ibuprofen.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul National University Bundang Hospital
Seongam, Gyeonggi-do, 13620, South Korea
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Other studies related to the condition(s) this trial covers.
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